Balthasar, Joseph: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling

Amidon, Gregory E., Anderson, Bradley D., Balthasar, Joseph P., Bergstrom, Christel A.S., Huang, Shiew-Mei, Kasting, Gerald, Kesisoglou, Filippos, Khinast, Johannes G., Mager, Donald E., Roberts, Chri

Journal:

Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 308 KB

english, 2018

2

Pharmacokinetic–pharmacodynamic modeling of methotrexate-induced toxicity in mice

Evelyn D. Lobo, Joseph P. Balthasar

Journal:

Journal of Pharmaceutical Sciences

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

3

Antibody pharmacokinetics and pharmacodynamics

Evelyn D. Lobo, Ryan J. Hansen, Joseph P. Balthasar

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 269 KB

english, 2004

4

Physiologically-based pharmacokinetic modeling to predict the clinical pharmacokinetics of monoclonal antibodies

Glassman, Patrick M., Balthasar, Joseph P.

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2016

Language:

english

File:

PDF, 2.29 MB

english, 2016

5

Physiologically-based modeling of monoclonal antibody pharmacokinetics in drug discovery and development

Glassman, Patrick M., Balthasar, Joseph P.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2018

Language:

english

File:

PDF, 1.07 MB

english, 2018

6

Pharmacokinetic/pharmacodynamic modeling of the effects of intravenous immunoglobulin on the disposition of antiplatelet antibodies in a rat model of immune thrombocytopenia

Ryan J. Hansen, Joseph P. Balthasar

Journal:

Journal of Pharmaceutical Sciences

Year:

2003

Language:

english

File:

PDF, 143 KB

english, 2003

7

Second-generation minimal physiologically-based pharmacokinetic model for monoclonal antibodies

Cao, Yanguang, Balthasar, Joseph P., Jusko, William J.

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2013

Language:

english

File:

PDF, 437 KB

english, 2013

8

Investigation of the Influence of Nephropathy on Monoclonal Antibody Disposition: A Pharmacokinetic Study in a Mouse Model of Diabetic Nephropathy

Engler, Frank A., Zheng, Bo, Balthasar, Joseph P.

Journal:

Pharmaceutical Research

Year:

2014

Language:

english

File:

PDF, 269 KB

english, 2014

9

Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry

Qu, Miao, An, Bo, Shen, Shichen, Zhang, Ming, Shen, Xiaomeng, Duan, Xiaotao, Balthasar, Joseph P., Qu, Jun

Journal:

Mass Spectrometry Reviews

Year:

2016

Language:

english

File:

PDF, 2.61 MB

english, 2016

10

“Catch-and-Release” Anti-Carcinoembryonic Antigen Monoclonal Antibody Leads to Greater Plasma and Tumor Exposure in a Mouse Model of Colorectal Cancer

Engler, Frank A., Polli, Joseph Ryan, Li, Tommy, An, Bo, Otteneder, Michael, Qu, Jun, Balthasar, Joseph P.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2018

Language:

english

File:

PDF, 869 KB

english, 2018

11

Intravenous Immunoglobulin Mediates an Increase in Anti-Platelet Antibody Clearance via the FcRn Receptor

Hansen, Ryan, Balthasar, Joseph

Journal:

Thrombosis and Haemostasis

Year:

2002

Language:

english

File:

PDF, 43 KB

english, 2002

12

Physiologically Based Modeling of the Pharmacokinetics of “Catch-and-Release” Anti-Carcinoembryonic Antigen Monoclonal Antibodies in Colorectal Cancer Xenograft Mouse Models

Polli, Joseph Ryan, Engler, Frank A., Balthasar, Joseph P.

Journal:

Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 1.82 MB

english, 2018

13

Application of Physiologically Based Pharmacokinetic Modeling to Predict the Effects of FcRn Inhibitors in Mice, Rats, and Monkeys

Li, Tommy, Balthasar, Joseph P.

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

File:

PDF, 1.92 MB

2019

14

Prediction of drug bioavailability in humans using immobilized artificial membrane phosphatidylcholine column chromatography and in vitro hepatic metabolic clearance

Beom Soo Shin, Chi Ho Yoon, Joseph P. Balthasar, Bu Young Choi, Seok Hyun Hong, Hyoung Jun Kim, Jong Bong Lee, Sang Wook Hwang, Sun Dong Yoo

Journal:

Biomedical Chromatography

Year:

2009

Language:

english

File:

PDF, 487 KB

english, 2009

15

A GPIIb/IIIa bioreactor for specific treatment of immune thrombocytopenic purpura, an autoimmune disease. Preparation, in vitro characterization, and preliminary proof-of-concept animal studies

Emel Emregul, Allan David, Joseph P. Balthasar, Victor C. Yang

Journal:

Journal of Biomedical Materials Research Part A

Year:

2005

Language:

english

File:

PDF, 201 KB

english, 2005

16

Oral supplementation with 25(OH)D3 versus vitamin D3: Effects on 25(OH)D levels, lower extremity function, blood pressure, and markers of innate immunity

Heike Annette Bischoff-Ferrari, Bess Dawson-Hughes, Elisabeth Stöcklin, Eduard Sidelnikov, Walter Churchill Willett, John Orav Edel, Hannes Balthasar Stähelin, Swen Wolfram, Alexander Jetter, Joseph S

Journal:

Journal of Bone and Mineral Research

Year:

2012

Language:

english

File:

PDF, 220 KB

english, 2012

17

Application of pharmacokinetic–pharmacodynamic modeling to predict the kinetic and dynamic effects of anti-methotrexate antibodies in mice

Evelyn D. Lobo, David M. Soda, Joseph P. Balthasar

Journal:

Journal of Pharmaceutical Sciences

Year:

2003

Language:

english

File:

PDF, 263 KB

english, 2003

18

Pharmacokinetic effects of 4C9, an anti-FcRn antibody, in rats: Implications for the use of FcRn inhibitors for the treatment of humoral autoimmune and alloimmune conditions

Kate E. Getman, Joseph P. Balthasar

Journal:

Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 196 KB

english, 2005

19

Application of anti-methotrexate Fab fragments for the optimization of intraperitoneal methotrexate therapy in a murine model of peritoneal cancer

Evelyn D. Lobo, Joseph P. Balthasar

Journal:

Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 107 KB

english, 2005

20

Physiologically based pharmacokinetic model for T84.66: A monoclonal anti-CEA antibody

Shweta R. Urva, Victor C. Yang, Joseph P. Balthasar

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 322 KB

english, 2010

21

High-affinity rabbit antibodies directed against methotrexate: Production, purification, characterization, and pharmacokinetics in the rat

Joseph P. Balthasar, Ho-Leung Fung

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 735 KB

english, 1995

22

Investigation of antibody-coated liposomes as a new treatment for immune thrombocytopenia

Rong Deng, Joseph P. Balthasar

Journal:

International Journal of Pharmaceutics

Year:

2005

Language:

english

File:

PDF, 320 KB

english, 2005

23

Strategies for improving the functionality of an affinity bioreactor

Tanya Wang, Zhiqiang Yang, Emel Emregul, Allan David, Joseph P. Balthasar, Junfeng Liang, Victor C. Yang

Journal:

International Journal of Pharmaceutics

Year:

2005

Language:

english

File:

PDF, 179 KB

english, 2005

24

High-performance liquid chromatographic assay for the determination of total and free topotecan in the presence and absence of anti-topotecan antibodies in mouse plasma

Jin Chen, Joseph P. Balthasar

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 335 KB

english, 2005

25

Sensitive high performance liquid chromatographic assay for assessment of doxorubicin pharmacokinetics in mouse plasma and tissues

Shweta R. Urva, Beom Soo Shin, Victor C. Yang, Joseph P. Balthasar

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 464 KB

english, 2009

26

Highly sensitive high-performance liquid chromatographic assay for methotrexate in the presence and absence of anti-methotrexate antibody fragments in rat and mouse plasma

Evelyn D Lobo, Joseph P Balthasar

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1999

Language:

english

File:

PDF, 265 KB

english, 1999

27

An ELISA for quantification of murine IgG in rat plasma: application to the pharmacokinetic characterization of AP-3, a murine anti-glycoprotein IIIa monoclonal antibody, in the rat

Ryan J Hansen, Joseph P Balthasar

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1999

Language:

english

File:

PDF, 90 KB

english, 1999

28

Determination of roxatidine in human plasma by liquid chromatography/electrospray mass spectrometry and application to a clinical pharmacokinetic study

Beom Soo Shin, Jin Won Choi, Joseph P. Balthasar, Deok Ki Hong, Jung Jun Kim, Sun Dong Yoo

Journal:

Rapid Communications in Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 238 KB

english, 2007

29

Prediction of human pharmacokinetics and tissue distribution of apicidin, a potent histone deacetylase inhibitor, by physiologically based pharmacokinetic modeling

Beom Soo Shin, Jürgen B. Bulitta, Joseph P. Balthasar, Minki Kim, Yohan Choi, Sun Dong Yoo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 446 KB

english, 2011

30

Evaluation of combined bevacizumab and intraperitoneal carboplatin or paclitaxel therapy in a mouse model of ovarian cancer

Dhaval K. Shah, Jean Veith, Ralph J. Bernacki, Joseph P. Balthasar

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.76 MB

english, 2011

31

Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice

Amit Garg, Joseph P. Balthasar

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2007

Language:

english

File:

PDF, 396 KB

english, 2007

32

Mathematical modeling of topotecan pharmacokinetics and toxicodynamics in mice

Jin Chen, Qiang Lu, Joseph P. Balthasar

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2007

Language:

english

File:

PDF, 2.18 MB

english, 2007

33

Physiologically based pharmacokinetic model for topotecan in mice

Dhaval K. Shah, Joseph P. Balthasar

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2011

Language:

english

File:

PDF, 354 KB

english, 2011

34

IVIG effects on autoantibody elimination

Ryan J. Hansen, Joseph P. Balthasar

Journal:

Year:

2004

Language:

english

File:

PDF, 48 KB

english, 2004

35

Inverse targeting of peritoneal tumors: Selective alteration of the disposition of methotrexate through the use of anti-methotrexate antibodies and antibody fragments

Joseph P. Balthasar, Ho-Leung Fung

Journal:

Journal of Pharmaceutical Sciences

Year:

1996

Language:

english

File:

PDF, 280 KB

english, 1996

36

Application of Pharmacodynamic Modeling for Designing Time-Variant Dosing Regimens to Overcome Nitroglycerin Tolerance in Experimental Heart Failure

John Anthony Bauer, Joseph P. Balthasar, Ho-Leung Fung

Journal:

Pharmaceutical Research

Year:

1997

File:

PDF, 534 KB

1997

37

Pharmacodynamics ofin VivoNitroglycerin Tolerance in Normal Conscious Rats: Effects of Dose and Dosing Protocol

Ellen Q. Wang, Joseph P. Balthasar, Ho-Leung Fung

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 122 KB

english, 2004

38

Pharmacokinetic and pharmacodynamic effects of high-dose monoclonal antibody therapy in a rat model of immune thrombocytopenia

Feng Jin, Zia R. Tayab, Joseph P. Balthasar

Journal:

The AAPS Journal

Year:

2005

Language:

english

File:

PDF, 220 KB

english, 2005

39

Pharmacodynamic modeling of chemotherapeutic effects: Application of a transit compartment model to characterize methotrexate effects in vitro

Evelyn D. Lobo, Joseph P. Balthasar

Journal:

The AAPS Journal

Year:

2002

Language:

english

File:

PDF, 342 KB

english, 2002

40

Investigation of the Influence of FcRn on the Distribution of IgG to the Brain

Amit Garg, Joseph P. Balthasar

Journal:

The AAPS Journal

Year:

2009

Language:

english

File:

PDF, 123 KB

english, 2009

41

AAPS Workshop Report: Strategies to Address Therapeutic Protein–Drug Interactions during Clinical Development

Sandhya Girish, Steven W Martin, Mark C Peterson, Lei K. Zhang, Hong Zhao, Joseph Balthasar, Raymond Evers, Honghui Zhou, Min Zhu, Lewis Klunk, Chao Han, Eva Gil Berglund, Shiew-Mei Huang, Amita Joshi

Journal:

The AAPS Journal

Year:

2011

Language:

english

File:

PDF, 464 KB

english, 2011

42

Pharmacokinetic and pharmacodynamic optimization of intraperitoneal chemotherapy

Joseph P. Balthasar, Ho-Leung Fung

Journal:

Year:

1996

Language:

english

File:

PDF, 811 KB

english, 1996

43

Nano-scale liquid chromatography/mass spectrometry and on-the-fly orthogonal array optimization for quantification of therapeutic monoclonal antibodies and the application in preclinical analysis

Xiaotao Duan, Lipeng Dai, Shang-Chiung Chen, Joseph P. Balthasar, Jun Qu

Journal:

Journal of Chromatography A

Year:

2012

Language:

english

File:

PDF, 832 KB

english, 2012

44

Mechanisms of Intravenous Immunoglobulin Action in Immune Thrombocytopenic Purpura

Feng Jin, Joseph P. Balthasar

Journal:

Human Immunology

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

45

Pharmacokinetic/pharmacodynamic modeling of IVIG effects in a murine model of immune thrombocytopenia

Rong Deng, Joseph P. Balthasar

Journal:

Journal of Pharmaceutical Sciences

Year:

2007

Language:

english

File:

PDF, 195 KB

english, 2007

46

Application of knockout mouse models to investigate the influence of FcγR on the tissue distribution and elimination of 8C2, a murine IgG1 monoclonal antibody

Lubna Abuqayyas, Joseph P. Balthasar

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

47

Pharmacokinetic mAb–mAb Interaction: Anti-VEGF mAb Decreases the Distribution of Anti-CEA mAb into Colorectal Tumor Xenografts

Abuqayyas, Lubna, Balthasar, Joseph P.

Journal:

The AAPS Journal

Year:

2012

Language:

english

File:

PDF, 519 KB

english, 2012

48

Application of PBPK modeling to predict monoclonal antibody disposition in plasma and tissues in mouse models of human colorectal cancer

Lubna Abuqayyas, Joseph P. Balthasar

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2012

Language:

english

File:

PDF, 1.53 MB

english, 2012

49

Evaluation of a Catenary PBPK Model for Predicting theIn VivoDisposition of mAbs Engineered for High-Affinity Binding to FcRn

Yang Chen, Joseph P. Balthasar

Journal:

The AAPS Journal

Year:

2012

Language:

english

File:

PDF, 311 KB

english, 2012

50

Predicting the effects of 8C2, a monoclonal anti-topotecan antibody, on plasma and tissue disposition of topotecan

Shah, Dhaval K., Balthasar, Joseph P.

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2014

Language:

english

File:

PDF, 532 KB

english, 2014